With the rapid development of green energies and the urgent need to find sustainable alternatives to conventional fossil fuels, biological fermentation processes have a very bright future ahead. Here is how modern Micro Gas Chromatography (Micro GC) is playing a pivotal role in optimizing these biological innovations, specifically through high-throughput screening.
Thanks to its state-of-the-art biotransformation and culture platform, combined with the deep expertise of its engineering team, TWB (Toulouse White Biotechnology) offers its partners and clients a fully automated, high-capacity screening service. This advanced setup allows for the simultaneous cultivation and monitoring of microorganisms across 24 parallel micro-reactors (50mL each).
To monitor these complex biological reactions, the platform required a robust and rapid analytical solution. By installing two Micro GC Fusion analyzers paired with automated stream selection valves, the TWB platform now boasts an unprecedented capacity for online gas analysis across all 24 micro-reactors.
Today, the production of light gas molecules—such as hydrogen, methane, and isobutene—is a major strategic challenge for the energy and transportation sectors amidst the global energy transition.
Fermentation stands out as one of the most promising production methods, particularly for the efficient valorization of biomass.
Thanks to the Micro GC Fusion,, biologists can now continuously monitor the real-time gas production and consumption of every individual reactor.
Speed and footprint are critical in a high-throughput laboratory environment. The analytical performance of this setup is highly efficient:- Rapid Run Times: Gas analysis is completed in under one minute per reactor.- High-Frequency Monitoring: The monitoring frequency for each specific biological environment is -approximately every 10 minutes.
Using an automated multi-position selection valve provides the perfect compromise between the number of high-end analyzers required and the desired analytical frequency for each reactor.
With two identical sets—each comprising one stream selection valve and one Micro GC Fusion—the customized solution proposed by CHEMLYS perfectly met TWB's strict requirements regarding laboratory footprint, analysis frequency, and budget.
We extend our sincere thanks to the entire TWB team for their warm welcome and their shared enthusiasm for implementing innovative analytical technologies!